Conn's syndrome is caused due to increased secretion of aldosterone from the adrenal glands. It could be because of an adrenal adenoma or adrenal hyperplasia. Excessive aldosterone levels lead to water retention, hypertension, and hypokalemia. We hereby report a case of a 37-year-old female who presented to the emergency department with quadriparesis and malignant hypertension. On investigating, she was found to have hypokalemia, metabolic alkalosis, rhabdomyolysis, raised aldosterone levels, and a right adrenal adenoma in the CT abdomen. Hypokalemia was treated and she was started on tablet spironolactone. She underwent laparoscopic adrenalectomy under general anesthesia. Her perioperative course was uneventful. Anesthesia management of a case of Conn's syndrome presents various challenges for the anesthesiologist. Good coordination between anesthesiologists, endocrinologists, and surgeons is required for the successful management of such a case.
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