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VOLUME 6 , ISSUE 2 ( July-December, 2021 ) > List of Articles

Original Article

A Prospective Randomized Study to Evaluate the Analgesic Efficacy and Quality of Recovery of Perioperative Intravenous Lignocaine Infusion in Laparoscopic Surgeries

Priyabrat Karan, Nita D'souza, Rajendra Patil

Keywords : Analgesia, Laparoscopic surgeries, Lignocaine

Citation Information : Karan P, D'souza N, Patil R. A Prospective Randomized Study to Evaluate the Analgesic Efficacy and Quality of Recovery of Perioperative Intravenous Lignocaine Infusion in Laparoscopic Surgeries. Res Inno Anesth 2021; 6 (2):36-43.

DOI: 10.5005/jp-journals-10049-0098

License: CC BY-NC 4.0

Published Online: 26-11-2021

Copyright Statement:  Copyright © 2021; The Author(s).


Background: The role of intravenous lignocaine perioperatively is studied to evaluate whether it has an opioid-sparing effect, component of a multimodal analgesia regimen, enhancing recovery, and early discharge of the patients undergoing laparoscopic surgery. Materials and methods: A randomized prospective double-blind study was done on 80 ASA I/II adult patients of both sexes in the age group 18–60 years scheduled for elective laparoscopic surgery under general anesthesia over a period of 6 months. Group L was administered lignocaine 1.5 mg/kg i.v. bolus followed by and 1.5 mg/kg/hour i.v. infusion and group NS 10 mL of 0.9% normal saline i.v. instead of lignocaine. Results: The intubation response, length of hospital stay, ambulation time, time of the return of bowel movements, use of rescue analgesics, use of opioids, and visual analog scores (VAS) in the saline group were significantly higher as compared to the lignocaine group. Conclusion: Intravenous lignocaine as bolus and infusion demonstrated a significant decrease in the hemodynamic parameters following intubation and postextubation, provided opioids-sparing role, showed lower VAS scores, fewer rescue analgesics over 24 hours, significantly early bowel movements, ambulation, and discharge.

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