Journal of Research & Innovation in Anesthesia

Register      Login

VOLUME 5 , ISSUE 1 ( January-June, 2020 ) > List of Articles

CASE REPORT

Anesthesia Management of a Child with Duchenne's Muscular Dystrophy Posted for Skin Grafting

Apeksha A Gala

Keywords : Caudal anesthesia, Duchenne\'s muscular dystrophy, Skin grafting

Citation Information : Gala AA. Anesthesia Management of a Child with Duchenne's Muscular Dystrophy Posted for Skin Grafting. Res Inno in Anesth 2020; 5 (1):13-14.

DOI: 10.5005/jp-journals-10049-0079

License: CC BY-NC 4.0

Published Online: 28-01-2021

Copyright Statement:  Copyright © 2020; Jaypee Brothers Medical Publishers (P) Ltd.


Abstract

Children with neuromuscular diseases may often present for anesthesia either as a part of a diagnostic procedure or surgery relating to their underlying disorder or for incidental surgery. The diagnosis may be clear from either a family history or from the clinical and pathological features. We managed to successfully anesthetize an 8-year-old male child who was a known case of Duchenne\'s muscular dystrophy and was posted for skin grafting surgery of his right lower limb. We would like to emphasize here the benefits of regional anesthesia, in such cases, (caudal in this case) which to a great extent reduces the requirement of general anesthetics used in the procedure, apart from giving adequate analgesia to the patients.


PDF Share
  1. Hoffman EP, Brown Jr RH, Kunkel LM. Dystrophin: the protein product of the Duchenne muscular dystrophy locus. Cell 1987;51(6):919–928. DOI: 10.1016/0092-8674(87)90579-4.
  2. Birnkrant DJ, Panitch HB, Benditt JO, et al. American College of Chest Physicians consensus statement on the respiratory and related management of patients with Duchenne muscular dystrophy undergoing anesthesia or sedation. Chest 2007;132(6):1977–1986. DOI: 10.1378/chest.07-0458.
  3. Hayes J, Veyckemans F, Bissonnette B. Duchenne muscular dystrophy: An old anesthesia problem revisited. Paediatr Anaesth 2008;18(2):100–106. DOI: 10.1111/j.1460-9592.2007.02302.x.
  4. Boltshauser E, Steinmann B, Meyer A, et al. Anaesthesia induced rhabdomyolysis in Duchenne muscular dystrophy. Br J Anaesth 1980;52(5):559. DOI: 10.1093/bja/52.5.559-a.
  5. Schmidt J, Muenster T, Wick S, et al. Onset and duration of mivacurium induced neuromuscular block in patient with Duchenne muscular dystrophy. Br J Anaesth 2005;95(6):769–772. DOI: 10.1093/bja/aei249.
  6. Blake DJ, Kroger S. The neurobiology of Duchenne muscular dystrophy: learning lesions from muscles. Trends Neurosci 2000;23(3):92–99. DOI: 10.1016/s0166-2236(99)01510-6.
  7. Grady RM, Zhou H, Cunningham JM, et al. Maturation and maintenance of neuromuscular synapse: genetic evidence for roles of dystrophin glycoprotein complex. Neuron 2000;25(2):279–293. DOI: 10.1016/s0896-6273(00)80894-6.
  8. Aldwinckle RJ, Carr AS. The anaesthetic management of patient with Emery Dreifuss muscular dystrophy for orthopaedic surgery. Can J Anaesth 2002;49(5):467–470. DOI: 10.1007/BF03017922.
PDF Share

© Jaypee Brothers Medical Publishers (P) LTD.