Coffin–Siris syndrome (CSS) is a rare genetic condition with characteristic musculoskeletal abnormalities and growth restrictions, coarse facial features, feeding abnormalities, systemic malformation, and developmental and cognitive delay.1–3 Main anesthetic concerns should be difficult airway that tends to get worse with age, risk of aspiration, and periop pulmonary complications in uncooperative and mentally retarded patients. We report a case of 9-years-old male patient with CSS for dental extraction and restoration under general anesthesia.
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